原雪峰
发布时间:2017-02-27 | 浏览次数: | 文章作者: | 发布人:植保学院

 

 

1.个人简介:

    原雪峰,山东省莱州市人,中共党员,山东农业大学植保学院教授,博士生导师;植物保护学院植物病理学系系主任,植物病理学系党支部副书记。2000.9-2005.7中国农业大学生物学院攻读硕博连读研究生理学博士,2005.7-2007.3中国农业大学农学与生物技术学院博士后流动站博士后,2007.3-2012.3美国University of Maryland细胞生物学与分子遗传学系访问学者。2012年山东农业大学特聘教授。在教学方面承担《植物保护学B》、《植病研究技术》、《植保专业英语》、《植检专业英语》、《植物检疫学》等本科生课程和《高级植物病理学》、《分子植物病理学》、《植物病毒学》等研究生课程。主持国家自然科学基金、山东省自然科学基金等项目,参与美国NSFNIH资助项目。长期从事植物RNA病毒的分子进化与基因表达调控机理研究,在《RNA》、《Journal of Virology 》、《Virology》、《Journal of General Virology 》等杂志上发表SCI论文20余篇;获专利一项。中国植物病理学会青年委员会委员,山东植物病理学会秘书长,美国病毒学会(ASV)会员。国家自然基金委、国家留学基金委、中国博士后科学基金评审专家、泰安市高端人才智库专家。

2.研究方向:

  1. 植物RNA病毒的分子进化(涉及RNA病毒基因组序列的分子进化及核心功能蛋白的活性变化)

  2. 植物RNA病毒的基因表达调控(着重研究病毒RNA结构在病毒基因组复制和病毒编码蛋白翻译中的作用)

3.期刊论文、会议报告:

   代表性论文(均为第一或通讯作者)

  1. Zhang Z, Wang D, Yu C, Wang Z, Dong J, Shi K*, Yuan X*. 2016. Identification of three new isolates of Tomato spotted wilt virus from different hosts in China: molecular diversity, phylogenetic and recombination analyses. Virology Journal (*并列通讯作者)

  2. 王国鲁,王德亚,于成明,原雪峰*. 2016. 烟草丛顶病毒ORF1蛋白的多克隆抗体制备及应用. 植物病理学报.46 (1)63-71.

  3. Wang D, Yu C, Wang G, Shi K, Li F, Yuan X*. 2015. Phylogenetic and recombination analysis of Tobacco bushy top virus in China. Virology Journal 12:111  doi:10.1186/s12985-015-0340-2

  4. Yuan X, Shi K, Simon AE. 2012. A local, interactive network of 3’ RNA elements supports translation and replication of Turnip Crinkle Virus.Journal ofVirology 86 (8): 4065-4081. 

  5. Stupina VA†, Yuan X†, Meskauskas A, Dinman JD, Simon AE.2011. Ribosome binding to a 5’ translational enhancer is altered in the presence of the 3’UTR in cap-independent translation of Turnip Crinkle Virus. Journal of Virology 85(10): 4638-4653.(† 并列第一作者)

  6. Yuan X†, Shi K†, Young MY, Simon AE. 2010. The terminal loop of a 3′ proximal hairpin plays a critical role in replication and the structure of the 3′ region of Turnip Crinkle Virus. Virology 402(2): 271-280. († 并列第一作者)

  7. Yuan X, Shi K, Meskauskas A, Simon AE. 2009. The 3′ end of Turnip Crinkle Virus contains a highly interactive structure including a translational enhancer that is disrupted by binding to the RNA-dependent RNA polymerase. RNA 15(10): 1849-1864.

  8. Yuan X†,Cao Y†, Xi D, Han C, Li D, Yu J. 2006. Analysis of the subgenomic RNAs and the small open reading frames of Beet Black Scorch Virus. Journal of General Virology 87(10): 3077-3086. (†并列第一作者)

代表性会议报告

  1. Yuan xuefeng. Cap-independent translation of p35 in Tobacco bushy top virus. 中国植病学会2015年青年学术研讨会(2015.10.22-24, 山东泰安)

  2. Yuan xuefeng. Translation mechanism of replicase components encoded by Tobacco bushy top virus. 2015年泰山学术论坛“现代植物病理学与粮食生产专题” (20158.28-8.31,山东青岛)

  3. Yuan xuefeng. Translation mechanism of replicase components encoded by Tobacco bushy top virus.中国植物病理学会2015年学术年会(20157.22-7.25,海南海口)

  4. Yuan xuefeng. The translational frameshift mechanism of ORF2 in Tobacco bushy top virus and its natural variants. 中国植物病理学会2014年学术年会

  5. Wang D, Wang G, Yuan X. Two types of elements involved in the cap-independent translation of Tobacco bushy top virus. The 3rd international conference on biotic plant interactions (Yangling, China) 2013: 38.

  6. Yuan X, Simon AE. A loosely structured region and adjacent hairpin located upstream of an internal tRNA-shaped structure in Turnip crinkle virus are critical components of translation and replication. American Society for Virology (30th Annual Meeting) 2011: 189.

  7. Yuan X, Shi K, Young MY, Simon AE. Complex structural interactions in the 3′ UTR of Turnip crinkle virus control translation and transcription.American Society for Virology (29th Annual Meeting) 2010:117.

  8. Yuan X, Shi K, Young MY, Simon AE. A hairpin in the 3′ UTR of TCV has a central role in transaltion and replication. American Society for Virology (28th Annual Meeting) 2009:130.

  9. Yuan X, Shi K, Young MY, Simon AE. The cis-element involved in the conformational shift of 3′ UTR in TCV between translation and replication process. American Society for Virology (27th Annual Meeting) 2008: 202-203.

  10. Yuan X, Cao Y, Xi D, Guo L, Han C, Li D, Yu J. Analysis of the Subgenomic RNAs and the Small ORFs of Beet black scorch virus. The 6th symposium of the international working group on plant viruses with fungal vectors. 2005.

  11. Yuan X, Cao Y, Han C, Li D, Yu J. Localization of the subgenomic RNAs and functional analysis for the Triple-gene-block of Beet black scorch virus (BBSV). Proceedings of 5th Hangzhou International Symposium on Plant Pathology and Biotechnology.2004.


4.目前主持的科研课题

  1. 山东农业大学特聘教授科研启动费2012.04-2017.04

  2. 国家自然科学基金(面上项目31370179

    烟草丛顶病毒不依赖帽子翻译机制的RNA结构基础解析2014.01-2017.12

  3. 山东省自然科学基金(面上项目ZR2013CM015

    烟草丛顶病毒基因组复制调控的RNA结构基础研究2013.10-2016.10

5.联系方式:

   通信地址:山东省泰安市岱宗大街61号山东农业大学植物保护学院
   邮政编码:271018
   联系电话:0538-8205608(办公室)13563821615
   邮件地址:snowpeak77@163.com